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After the government has issued the patent to the inventor, the Patent Office is no longer responsible for the patent. It is the inventor's responsibility to maintain the patent, keep aware of the patent's expiration date, and monitor and prevent other people from infringing on the owner's rights to the patent.
The only time the Patent Office will make changes to the patent is if it is printed with incorrect information. Then the patent owner can apply to have this corrected if the error was the fault of the Patent Office. If the error was on the part of the inventor, then it can be corrected, for a fee.
After the patent has been approved, the person issued the patent has the right to do almost anything with it. Therefore, as an official document of ownership, it can be bequeathed to your next of kin, used as collateral for a loan, or sold to the highest bidder. It's your property, to dispose of as you see fit.
If you own a patent and would like to bequeath it to your next of kin or a close friend, this information should be included in your will along with the other property you plan to leave to family and friends. As a legal document, it can be bequeathed in the same way you would leave your house or other property to a son or daughter. Even though a patent is granted in the case of an invention, it is not unheard of for senior family members of large corporations to bequeath their patents to a son or daughter who will be running the family business after they have departed. This is usually seen when the product patented in the family business is quite popular, or when people would like to make an ongoing donation. For example, a person wanting to give to charity can bequeath profitable patents to the charity of their choice. Stipulating who will inherit your patents will ensure the safety of the company's products, and keep these inventions in the family for years to come.